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Neuropathy is one of the most common chroniccomplications in Diabetes Mellitus (DM), affecting 50% of patients sufferingfrom it. Its clinical features vary widely over an ample spectrum of signs andsymptoms whose treatment involves specialists in diverse fields, fromdermatologists and podiatrists to vascular surgeons. This kind of neuropathy ischaracterized by a progressive loss of nerve fibers which most commonly affectsthe peripheral nervous system.
Sinapsis therapy accelerate peripheral activation ofsensory nerves, resulting an excellent alternative for pain management
Michigan Neuropathy Screening Instrument
Please,take a few minutes to answer the following questions about the feeling in yourlegs and feet. Check yes or no based on how usually feel.

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1
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Are you legs and/or feet numb?
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□ Yes □ No
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2
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Do you ever have any burning pain in your legs and/or feet?
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□ Yes □ No
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3
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Are your feet too sensitive to touch?
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□ Yes □ No
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4
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Do you get muscle cramps in your legs and/or feet?
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□ Yes □ No
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5
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Do you ever have any prickling feelings in your legs or feet?
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□ Yes □ No
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6
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Does it hurt when the bed covers touch your skin?
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□ Yes □ No
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7
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When you get into the tub or shower, are you able to tell the hot water from the cold water?
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□ Yes □ No
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8
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Have you ever had an open sore on your foot?
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□ Yes □ No
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9
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Has your doctor ever told you that you have diabetic neuropathy?
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□ Yes □ No
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10
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Do you feel weak all over most of the time?
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□ Yes □ No
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11
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Are your symptoms worse at night?
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□ Yes □ No
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12
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Do your legs hurt when you walk?
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□ Yes □ No
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13
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Are you able to sense your feet when you walk?
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□ Yes □ No
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14
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Is the skin on your feet so dry that it cracks open?
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□ Yes □ No
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15
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Have you ever had an amputation?
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□ Yes □ No
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